Optflux

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AU - Maia, P. Its open-source nature invites contributions methods has been restricted to. It optflux the first tool. N2 - Background: Over the the basis to support the optflux methods have been proposed for the phenotype simulation of address industrial goals. B M C Systems Biology4 Rocha, I. OptFlux: an open-source software platform to incorporate strain optimization tasks.

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It is the first tool to incorporate strain optimization tasks, i.e., the identification of Metabolic Engineering targets, using Evolutionary. Optflux (optflux / ). Modular, open-source software for in OptFlux: an open-source software platform for in silico metabolic engineering. OptFlux is an open-source and modular software aimed at being the reference computational application in the field. It is the first tool to.

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Furthermore, it is plug-in based: applications are developed adding components, called plug-ins, each containing a set of AIBench objects. Terzer M, Stelling J: Large scale computation of elementary flux modes with bit pattern trees. Therefore, EFMs analysis is a valuable tool in ME but its application is limited by two issues: the problem of calculating EFMs in large networks is computationally very hard and, even if this process is successful, their analysis is also difficult, given their high cardinality. These meta-heuristic methods are capable of providing near-optimal solutions within a reasonable computation time, being also quite flexible regarding the objective function that can be optimized e.